Steroid Guide Review

IGF-1 is naturally produced in the liver as a result of GH (Growth Hormone) metabolism in the presence of insulin. Muscle tissue can also produce IGF-1 by way of an intracellular response. In fact, one of the benefits of training sets that result in an intense burn, or stretch position training, is the production of natural IGF-1. It is also a side effect of oral 17-ALFA ALKYLATED STEROIDS, which cause a higher release of IGF-1 from the liver. IGF-1 receptors exist throughout muscles and organs such as the heart, spleen, small intestines, and kidneys with a higher concentration of receptors exerting effects upon organs. IGF-1 is extremely anabolic, far more so than GH or Insulin.

Recombinant IGF-1 (genetically engineered) was reported to be effective when injected intramuscularly because it causes localized growth. This was the most popular method, and the agreed wisest for the most part. The drug has a half-life of about 10 minutes, and if it is or has been bound to IGF -BP-3, (INSULIN GROWTH FACTOR BINDING PROTEIN) the half- life is extended to about 12 hours. Pro’s often stacked Insulin and/or GH with IGF-1 because IGF-1 shuts off natural GH production and GH causes Insulin resistance. IGF-1 is often referred to as Pro-insulin because it counteracts Insulin resistance and interacts with insulin. But this would actually be an untrue term for IGF-1.
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Transdermal testosterone comes as a patch to apply to the skin. It is usually applied once daily, and the schedule depends on the type of patch. Androderm patches are applied each night between 8 pm and midnight and left on for 24 hours. Testoderm patches are applied at the same time every morning (or any other regular time of day or night if the morning is inconvenient) and left on for 22-24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use testosterone patches exactly as directed. Do not apply more or fewer patches or apply the patches more often than prescribed by your doctor.

Androderm and Testoderm brand patches both contain testosterone, but they are manufactured differently and are intended for use on different parts of the body. Be sure you know which type of patch you are using and where, when, and how you are to apply your patches. Carefully read the manufacturer’s patient information that comes with your patches.

If you are using Androderm patches, you should choose a spot on your back, stomach, thighs, or upper arms to apply your patch(es). Be sure that the spot you have chosen is not oily, hairy, likely to perspire heavily, over a bone such as a shoulder or hip, or likely to be under pressure from sitting or sleeping. Do not apply to the scrotum or a skin area with open sores or irritation. Also be sure that the patch will stay flat against the skin and will not be pulled or stretched during normal activity. Choose a different spot each night and wait at least 7 days before applying another patch to a spot you have used. more…

Human Growth Hormone (HGH)
(somatotropin)

Human growth hormone (Somatotropin) is produced in the body by the pituitary gland. Before this happens, Growth Hormone Releasing Hormone (HGHRH) and Somatostatin (SST) are released by the hypothalamus, and that determines whether more or less HGH is produced by the pituitary.(1) Many factors influence the release of HGH, however, including nutrition and exercise (6)(7).

Once it is released, Human Growth Hormone (HGH), which is also called Somatotropin (STH) has many functions in the human body. HGH is a protein that stimulates the body cells to increase both in size, as well as undergo more rapid cell division than usual. In addition, it enhances the movement of amino acids through cell membranes and also increases the rate at which these cells convert these molecules into proteins. Clearly, you can see that this would amount to an anabolic (muscle building) effect in the human body.

HGH also has the ability to cause cells to decrease the normal rate at which they utilize carbohydrates, and simultaneously increase the rate at which they use fats.(1) Fat loss and lean mass increases with HGH have been found at a dose as low as . 0.028 iu/kg/daily for 24 weeks (4), however, in my estimation, that would be insufficient for a bodybuilder trying to gain muscle. Let´s use .028iu/kg as a working number; that´s 2.8iu for a 100kg (220lbs) bodybuilder. That´s certainly not unreasonable, and I would say that that dose to 2x that dose is the range most bodybuilders and athletes are finding their best results with.

Also, that length of time used in the study I just mentioned (24 weeks) is very typical of HGH use, and in conversations with my friends who have used this compound, have told me that they experience consistent results starting well after the 2-month-mark, and they tend to either run this stuff for 6 months at a time, or year-round (if they have sufficient funds).

One of my friends is able to consistently retain a shredded 6-7% body fat all year round with the assistance of HGH, whether he is on steroids or off. He also has noted that his cardio (fast walking, for an hour a day) was much easier while on HGH than when off, and certainly the research I´ve done would support his claim that sub maximal aerobic ability is improved with HGH use (5) (15).

How anabolic is this stuff? more…

Deca-Durabolin
(Nandrolone Decanoate)

Deca - Durabolin (”Deca”) is actually the brand name for Organon´s version of the compound Nandrolone Decanoate. This is a 19-Nor compound (some would say that it is the 19-nor compound), and as such, it shares basically the same characteristics with all of them. One thing unique to Deca, above nearly all steroids, is the mystique it has had for the last quarter of a century. On a personal level, I´ve included Deca in cycles at doses ranging from 100mgs/week to 2,000mgs per week. Suffice to say, I have my fair share of experience with this compound. This drug was regarded very highly by Dan Duchaine in his Underground Steroid Handbooks as well as many of his later writings. For many, this was and is the final word on Deca. Let´s delve into some of the reasons that Deca´s mystique may be well deserved.

First of all, Deca (and Nandrolone in general) doesn´t produce many estrogenic or androgenic side effects. This is because Deca has a very low rate of aromatization (conversion to estrogen via the aromatase enzyme), roughly equal to 20% the rate of Testosterone. more…

Androgel & Androderm

(testosterone)

Transdermal Testosterone has been marketed heavily in the Hormone Replacement Therapy Market for the last decade. For over 50 years, testosterone therapy has been used for the treatment of hypogonadism. In recent years, there has been an increase in the use of testosterone therapy for men with late-onset hypogonadism, sometimes referred to as andropause. Testosterone therapy in older and hypogonadic men can significantly improve their sense of well-being, and lead to increases in muscle and bone mass, upper body strength, virility and libido (5). Oral delivery of unmodified testosterone is not really a viable option, due to it´s rapid first-pass metabolism, possible liver toxicity, and its relatively short half-life. more…

Anadrol 50 (oxymetholone)

Anadrol 50(commonly called by athletes “A50″ or “A-bombs”) was initially developed as a compound to help people with anemia, and has since been used very successfully to aid people who are suffering from many other diseases where weight loss is a concern. Thus, it is clearly an effective agent for promoting weight gain, increasing appetite, gaining strength, and increasing Red Blood Cell count. And, as with most Anabolic/Androgenic Steroids (AAS), it has it´s downsides as well. Anadrol will inhibit your body´s natural production of hormones (testosterone, etc& ), will negatively affect your blood lipid profile, can cause water retention, is notorious for causing headaches, and is also highly liver toxic (in fact, it has the worst reputation for hepatoxicity out of all steroids). Paradoxically, although one the benefits touted by it´s original manufacturer (Syntex) is that it can be used to stimulate weight gain through increasing appetite, taking too much may actually inhibit your appetite! more…